EU glyphosate evaluation fails to acknowledge key mechanism that can lead to cancer

On 7 September EFFAT  along with other 15 member of the  European Coalition Stop Glyphosate, EFFAT sent an open letter to Health Commissioner Kyriakides to  highlighted that solely based on the cancer evidence glyphosate, the world’s most used herbicide, does not fulfil the criteria to be approved. 

A new scientific study reveals that ECHA dismissed important carcinogenicity findings and neglected evidence that glyphosate induces oxidative stress, a recognised mechanism that can lead to cancer. EFSA in its conclusion wrongfully relied on ECHA’s classification of glyphosate as ‘noncarcinogenic’. This is a critical failure, since accepting this scientific evidence would inevitably lead to the conclusion that the glyphosate authorisation cannot be prolonged under EU law.

On top of the evidence that glyphosate can cause oxidative stress, NGOs highlighted the following shortcomings in ECHA’s and EFSA’s assessment on carcinogenicity leading to its misclassification as a non-carcinogen:

  • There were statistically significant tumour incidences observed in animal cancer studies provided by the applicants (for the glyphosate EU re-authorization)
  • Two genotoxicity OECD protocol studies are absent from the applicants’ dossier;
  • EFSA is being deceitful by claiming a non existing “limit dose” in carcinogenicity assessment
  • Malignant lymphomas in animal studies complement the evidence on non-Hodgkin’s lymphoma in epidemiology studies.  

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PR__oxidative_stress_carcinogenity.docx
Letter to Commissionner Kyriakides – 7_09_2023 (1)

Stop Glyphosate Coalition